|Statement||edited by Johannes Myren and Morten H. Vatn.|
|Series||Scandinavian journal of gastroenterology : Supplement ;, 42, v. 11|
|Contributions||Myren, Johannes., Vatn, Morten H., Dumex (Firm)|
|LC Classifications||QP151 .G37|
|The Physical Object|
|Pagination||163 p. :|
|Number of Pages||163|
|LC Control Number||79304150|
transfused blood inhibited the recipient's gastric secretion (Table 1, Fig. 3). Themeaninhibition was 51 5%. The inhibition affected the volume of gastric juice andthe acid output, but no significant change in concentration of acid, of pepsin, or of electrolytes was seen. Secretion of free acid was completely inhibited in subject no. 2 (Table I Cited by: The introduction of potent inhibitors of acid secretion, that is the H 2-receptor blocking agent cimetidine and its analogues in the late seventies and the even more potent proton pump inhibitor (PPI) omeprazole and its analogues in the late eighties have revolutionized therapy. Surgery became superfluous for benign oesophagogastric diseases Cited by: 4. Search within book. Front Matter. Pages I-X. PDF. The discovery and development of the proton pump inhibitor. Front Matter. Pages PDF. Consequences of gastric acid inhibition in animals. Enar Carlsson, Niilo Havu. Pages Consequences of gastric acid inhibition in man. Werner Creutzfeldt. The results were presented at the ASCO Gastrointestinal Cancers Symposium and showed for the first time that PD-1 inhibition could lead to an improvement in overall survival for patients with heavily pretreated gastric or gastroesophageal cancer. 27 Median overall survival was months (95% CI, –) with nivolumab versus
The pre-cancerous gastric lesions and gastric cancers over-expressed cyclooxygenase (COX) This overexpression not only is associated with Helicobacter pylori infection, but also maybe due to exposure to carcinogens. Targeted inhibition of COX, especially the COX-2 isoform, can lead to growth inhibition and apoptosis of gastric cancer in vitro. Gastric inhibitory polypeptide receptor (GIPR) directly induces energy accumulation in adipose tissue in vitro. However, the importance of the direct effect of GIPR signaling on adipose tissue in vivo remains unclear. In the current study, we generated adipose tissue–specific GIPR knockout (GIPRadipo−/−) mice and investigated the direct actions of GIP in adipose tissue. Inhibition of Gastric Secretion by Other Post-Stomach Intestinal Factors. Although intestinal chyme slightly stimulates gastric secretion during the early intestinal phase of stomach secretion, it paradoxically inhibits gastric secretion at other times. This inhibition results from at . Gastric inhibitory polypeptide (GIP), or gastric inhibitory peptide, also known as glucose-dependent insulinotropic polypeptide (also abbreviated as GIP), is an inhibiting hormone of the secretin family of hormones. While it is weak inhibitor of gastric acid secretion, its main role is to stimulate insulin secretion.. GIP, along with glucagon-like peptide-1 (GLP-1), belongs to a class of.
These drugs (cimetidine, famotidine, available IV and orally; and nizatidine available orally) are competitive inhibitors of histamine at the H2 receptor, thus suppressing gastrin-stimulated acid secretion and proportionately reducing gastric juice volume. Histamine-mediated pepsin . Gastric Cancer, a joint official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, publishes significant studies related to stomach neoplasms. The journal welcomes original articles, case reports, short communications, and technical notes, which will be peer-reviewed by the editorial board. Pure gastric juice, as it is secreted by the fundus of the stomach, is an exceedingly corrosive liquid and has the capacity to digest away the normal mucous membrane of the stomach, duodenum, or small intestines and produce a defect indistinguishable from the chronic progressive peptic ulcers seen in patients. 1 The mucous membrane is exposed to such pure gastric juice, either when gastric. Gastric Inhibitory Polypeptide. by J. C. Brown. Monographs on Endocrinology (Book 24) Thanks for Sharing! You submitted the following rating and review. We'll publish them on Brand: Springer Berlin Heidelberg.